Liquid Dosage
Monoclonal Antibodies
GEA is a leading specialist in the field of process equipment for liquid processing and metering for the pharmaceutical and biotech industries, including fermentation plant for the manufacture of products such as monoclonal antibodies (mAbs) for diagnostic and therapeutic purposes.
Monoclonal antibodies are known as targeted therapies because they work by targeting specific proteins on the surface of cells. Successfully used to treat cancers, tumors and other serious diseases, mAbs are — compared with other biopharmaceutical products — large proteins that require relatively high administration doses and traditionally necessitate high-volume manufacturing equipment/systems and facilities. GEA offers production systems for monoclonal antibodies that are produced in state-of-the-art stainless steel bioreactors by specific cell cultures.
From Culture to Harvest
The cell culture process is done in several steps, starting with 10 L precultures and successively cultivating intermediate batches up to a final production volume of up to 20,000 L. These systems comprise the vessel, with the stirrer as the core element, and peripherals such as temperature control systems, clean-in-place (CIP) components, aeration and deaeration systems, input systems and automated sensors, actuators and the operator interface.
Support processes, such as media preparation and harvest systems are also available from GEA. The process integration of separators and filters for the harvest step is also within GEA’s scope of service. Because of the high sensitivity of the cells and the need for operator and product safety, all GEA system components are designed according to the latest standards and have the highest grade of finish quality.
产品与技术
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CIP/SIP 解决方案
GEA 创新的 CIP 理念可满足全方位的高标准要求。我们的专家可确保产品在每个工艺点的安全。我们的每一次升级都基于当地的情况和客户的具体要求，可为客户实现显著地成本节约。
Hygienic pumps
GEA Hilge 提供种类繁多的离心泵和容积泵，适用于饮料、食品和制药行业的各种敏感应用。
Lyophilizers (Pharma Freeze Dryers)
GEA's thorough understanding of the lyophilization process enables them to supply a comprehensive range of products and services, comprising laboratory equipment, pilot plants for research and small-scale production batches, industrial size pharmaceutical production freeze dryers.
喷雾干燥器
没有哪家公司比 GEA 更了解喷雾干燥。 我们的专业知识累积已接近一个世纪，其中我们已在全球设计并提供了超过 1 万台 GEA 干燥设备，并且为客户进行了更多试验。
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GEA 洞察
All pharmaceutical freeze-drying vials are the same! Aren't they?
Whether it’s a fad or the future, 100% vial traceability is becoming an increasingly important consideration in the pharmaceutical freeze drying industry. Keeping a close eye on developments is GEA. We’re investigating possible solutions and, what’s more, we have the experience, expertise and know-how to implement them.
Innovating patient care with aseptic spray drying
At GEA, our commitment to engineering for a better world fuels our pursuit of innovative solutions that enhance patient care and safety. One of our most promising ventures in recent years is aseptic spray drying – a technology that promises to revolutionize pharmaceutical manufacturing.
